USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P49773 USC-OGP 2-DE database:  P49773 P49773 General information about the entry View entry in simple text format Entry name HINT1_HUMAN Primary accession number P49773 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Histidine triad nucleotide-binding protein 1; EC=3.-.-.-; AltName: Full=Adenosine 5'-monophosphoramidase; AltName: Full=Protein kinase C inhibitor 1; AltName: Full=Protein kinase C-interacting protein 1; Short=PKCI-1;. Gene name Name=HINT1 Synonyms=HINT, PKCI1, PRKCNH1 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0596: pI=6.36; Mw=13027 PLATELET_6-11 {PLATELET 6-11} Homo sapiens (Human)   map experimental info   PLATELET_6-11 MAP LOCATIONS: SPOT OGP-1088: pI=6.41; Mw=15336 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1348: pI=6.78; Mw=14679 Cross-references UniProtKB/Swiss-Prot P49773; HINT1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name HINT1_HUMAN Primary accession number P49773 Secondary accession number(s) Q9H5W8 Sequence was last modified on  January 23, 2007 (version 2) Annotations were last modified on  March 15, 2017 (version 172) Name and origin of the protein Description RecName: Full=Histidine triad nucleotide-binding protein 1; EC=3.-.-.-; AltName: Full=Adenosine 5'-monophosphoramidase; AltName: Full=Protein kinase C inhibitor 1; AltName: Full=Protein kinase C-interacting protein 1; Short=PKCI-1; Gene name Name=HINT1 Synonyms=HINT, PKCI1, PRKCNH1 Encoded on Name=HINT1; Synonyms=HINT, PKCI1, PRKCNH1 Keywords 3D-structure; Acetylation; Apoptosis; Complete proteome; Cytoplasm; Direct protein sequencing; Disease mutation; Hydrolase; Neuropathy; Nucleotide-binding; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U27143; AAA82926.1; -; mRNA EMBL U51004; AAC71077.1; -; mRNA EMBL AK026557; BAB15500.1; -; mRNA EMBL CR457048; CAG33329.1; -; mRNA EMBL BC001287; AAH01287.1; -; mRNA EMBL BC007090; AAH07090.1; -; mRNA CCDS CCDS4147.1; -; . PIR S72501; S72501; . RefSeq NP_005331.1; NM_005340.6; . UniGene Hs.483305; -; . PDB 1AV5; X-ray; 2.00 A; A/B=2-126 PDB 1KPA; X-ray; 2.00 A; A/B=2-126 PDB 1KPB; X-ray; 2.00 A; A/B=2-126 PDB 1KPC; X-ray; 2.20 A; A/B/C/D=2-126 PDB 1KPE; X-ray; 1.80 A; A/B=2-126 PDB 1KPF; X-ray; 1.50 A; A=2-126 PDB 3TW2; X-ray; 1.38 A; A/B=1-126 PDB 4EQE; X-ray; 1.52 A; A/B=1-126 PDB 4EQG; X-ray; 1.52 A; A/B=1-126 PDB 4EQH; X-ray; 1.67 A; A/B=1-126 PDB 4ZKL; X-ray; 2.34 A; A/B/C/D=1-126 PDB 4ZKV; X-ray; 1.92 A; A/B/C/D=1-126 PDB 5ED3; X-ray; 1.31 A; A/B=1-126 PDB 5ED6; X-ray; 1.52 A; A/B=1-126 PDB 5EMT; X-ray; 1.50 A; A/B=1-126 PDB 5I2E; X-ray; 1.60 A; A/B=1-126 PDB 5I2F; X-ray; 1.25 A; A/B=1-126 PDBsum 1AV5; -; . PDBsum 1KPA; -; . PDBsum 1KPB; -; . PDBsum 1KPC; -; . PDBsum 1KPE; -; . PDBsum 1KPF; -; . PDBsum 3TW2; -; . PDBsum 4EQE; -; . PDBsum 4EQG; -; . PDBsum 4EQH; -; . PDBsum 4ZKL; -; . PDBsum 4ZKV; -; . PDBsum 5ED3; -; . PDBsum 5ED6; -; . PDBsum 5EMT; -; . PDBsum 5I2E; -; . PDBsum 5I2F; -; . ProteinModelPortal P49773; -; . SMR P49773; -; . BioGrid 109341; 75; . IntAct P49773; 11; . MINT MINT-5001048; -; . STRING 9606.ENSP00000304229; -; . BindingDB P49773; -; . ChEMBL CHEMBL5878; -; . DrugBank DB02162; 5'-O-(N-Ethyl-Sulfamoyl)Adenosine; . DrugBank DB03349; 8-Bromo-Adenosine-5'-Monophosphate; . DrugBank DB00131; Adenosine monophosphate; . DrugBank DB02183; Adenosine-5'-Ditungstate; . DrugBank DB01972; Guanosine-5'-Monophosphate; . iPTMnet P49773; -; . PhosphoSitePlus P49773; -; . SwissPalm P49773; -; . DMDM 1708543; -; . OGP P49773; -; . UCD-2DPAGE P49773; -; . EPD P49773; -; . MaxQB P49773; -; . PaxDb P49773; -; . PeptideAtlas P49773; -; . PRIDE P49773; -; . TopDownProteomics P49773; -; . Ensembl ENST00000304043; ENSP00000304229; ENSG00000169567; . GeneID 3094; -; . KEGG hsa:3094; -; . UCSC uc003kve.5; human; . CTD 3094; -; . DisGeNET 3094; -; . GeneCards HINT1; -; . HGNC HGNC:4912; HINT1; . HPA HPA044577; -; . MalaCards HINT1; -; . MIM 137200; phenotype; . MIM 601314; gene; . neXtProt NX_P49773; -; . OpenTargets ENSG00000169567; -; . Orphanet 324442; Autosomal recessive axonal neuropathy with neuromyotonia; . PharmGKB PA29286; -; . eggNOG KOG3275; Eukaryota; . eggNOG COG0537; LUCA; . GeneTree ENSGT00510000046448; -; . HOGENOM HOG000061064; -; . HOVERGEN HBG051906; -; . InParanoid P49773; -; . KO K02503; -; . OMA YRLITNN; -; . OrthoDB EOG091G1001; -; . PhylomeDB P49773; -; . TreeFam TF314862; -; . SABIO-RK P49773; -; . ChiTaRS HINT1; human; . EvolutionaryTrace P49773; -; . GeneWiki HINT1; -; . GenomeRNAi 3094; -; . PRO PR:P49773; -; . Proteomes UP000005640; Chromosome 5; . Bgee ENSG00000169567; -; . CleanEx HS_HINT1; -; . ExpressionAtlas P49773; baseline and differential; . Genevisible P49773; HS; . GO GO:0005856; C:cytoskeleton; TAS:ProtInc; . GO GO:0005829; C:cytosol; IDA:HPA; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0000118; C:histone deacetylase complex; IDA:UniProtKB; . GO GO:0005634; C:nucleus; IDA:HPA; . GO GO:0005886; C:plasma membrane; IDA:HPA; . GO GO:0016787; F:hydrolase activity; IDA:UniProtKB; . GO GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW; . GO GO:0005080; F:protein kinase C binding; TAS:ProtInc; . GO GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IMP:UniProtKB; . GO GO:0050850; P:positive regulation of calcium-mediated signaling; IEA:Ensembl; . GO GO:0009154; P:purine ribonucleotide catabolic process; IDA:UniProtKB; . GO GO:0006355; P:regulation of transcription; DNA-templated; IMP:UniProtKB GO GO:0007165; P:signal transduction; TAS:ProtInc; . GO GO:0006351; P:transcription; DNA-templated; IEA:UniProtKB-KW Gene3D 3.30.428.10; -; 1; . InterPro IPR019808; Histidine_triad_CS; . InterPro IPR001310; Histidine_triad_HIT; . InterPro IPR011146; HIT-like; . PANTHER PTHR23089; PTHR23089; 1; . Pfam PF01230; HIT; 1; . PRINTS PR00332; HISTRIAD; . SUPFAM SSF54197; SSF54197; 1; . PROSITE PS00892; HIT_1; 1; . PROSITE PS51084; HIT_2; 1; .

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